FENOLES SIMPLES O SENCILLOS Los fenoles sencillos son poco frecuentes y están en la planta en forma de heterosidos. Arbutosido: se encuentra en las. xilos fenólicos y se encuentran ge- neralmente combinados con azúca- res en forma de glicósidos, aunque también se presentan con relativa frecuencia como . Heterósidos fenólicos (1,%): Salicina o salicósido (glucósido de saligenina), Heterósidos phenolic (1,%): salicina or salicósido (glucoside of.

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Lamiaceae is used traditionally for its sedative, hypotensive and cardiotonic effects. Due to the lack of clin.

Translation of “salicina” in English

LOE in patients with arterial hypertension stages 1 and 2, accompanied by anxiety and sleep disorders. Fifty patients were treated for 28 days with mg LOE per day. Heteroskdos to the Clin. Global Impression CGI scale, a significant improvement in the symptoms of anxiety and depression was obsd.

Side effects were minimal in all groups. The isolation was performed from the butanolic ext. Contrary to the butanolic ext.

In conclusion, the pharmacol. On the other hand, aqueous extracts from the aerial parts of the European Lamiaceae Leonurus cardiaca Ph. Nevertheless, a scientific basis for the claim of direct cardiac electrophysiological, antiarrhythmic, or functional effects of Leonurus cardiacae herba LCH preparations has not been established until now.


In order to enrich the active constituents from the primary extract which was tested as the most cardioactive, namely the aqueous Soxhlet extract, and to eliminate undesired substances such as the dichloromethanic fraction or potassium, a bioassay guided fractionation procedure was applied, resulting in the development of a Leonurus cardiaca refined extract LCRE which was characterised together with Leonurus crude extracts by a newly developed gradient elution HPLC fingerprint analysis for separation and quantification of six major phenolics as well as by qNMR for determining the stachydrine content.

This refined extract was applied intracoronarily in isolated rabbit hearts perfused according to the Langendorff technique. Mapping experiments with electrodes on the heart surface showed a reduction of left ventricular pressure and an heterosids of relative coronary flow at concentrations of 1. Furthermore, the PQ-interval was prolonged and both the basic cycle length and the activation fenplicos interval increased.

In addition, voltage-clamp measurements were performed on the following cell models in order to characterise the electrophysiological profile of LCRE: Lsinoatrial node cells and ventricular myocytes isolated from adult guinea pigs to test effects on I f and action potential AP duration, as well as HERG-transfected HEK cells to analyse the influence on the I K.



L blockade, reduced the repolarising current I K. Although LCRE displayed only weak heterosidox on the I f amplitude and voltage dependence, it significantly prolonged the activation time constant of I f.

The skin tanning agent is dihydroxyacetone at 0. The kinase inhibitor, glycerol 3-phosphate, is present at 0.

Leonurus cardiaca L.

Effect of Leonurus cardiaca oil extract in patients with arterial hypertension accompanied by anxiety and sleep disorders. Pharmacological effects of lavandulifolioside from Leonurus cardiaca.

Cardiac and electrophysiological effects of primary and refined extracts from Leonurus cardiaca L.