PubMed journal article Chronic exposure to pyrethroid-based allethrin and However, SGPT activity increased significantly in persons exposed to only allethrin. It has been concluded that mitochondrial apoptosis by allethrin could be an important factor in decreased male fertility . Similarly, allethrin. Chronic exposure to pyrethroid-based allethrin and prallethrin mosquito repellents alters .. activity of the enzyme SGPT (51%) in allethrin-exposed subjects.
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Skip to main content. Log In Sign Up. Journal of Medicinal Plants Studies ; 3 6: Mosquito coils are widely used as mosquito repellent. These particles and cause the potential Department of Biochemistry, toxicological effects of the smoke on mammals. This study therefore aims to investigate the toxicological Maruthupandiyar College, effects of mosquito alletgrin smoke in rats with hope that the results would provide a guide line for proper use Thanjavur, Tamil Nadu, India.
Yamini Priya V Keywords: In most Balaji medical college, urban and rural areas of the country, mosquito populations are menacing throughout the year Chrompet, Chennai, Tamil Nadu, allerhrin for some attenuation during summer and winter mosquitoes transmit diseases such as India. Mosquito coils containing DDT Dichlora dipheryl trichloro ethane and other organophosphorus compounds were not effective in repelling mosquitoes.
Male albino rats weight about g were obtained from the Indian institute of science Bangalore, the animals were housed in polypropylene cages and maintained in controlled temperature with 12 hours period of light dark and fed with standard rad feed and water were provided adlibitum.
All other reagent and chemical used in this study was ssgpt analytical grade with high purity. Plant materials and Drug alleturin Hemidesmus indicus root were collected locality in the mouth at September to December The Hemidesmus indicus were shade dried and finally powdered which was sieved through nice cloths and used as drug.
Hemidesmus indicus Vernacular Name English: Indian Sarsaparilla country sarsaparilla Tamil: Nannari, Savibam Correspondence Sanskrit: Aloethrin, magrabu Biochemistry, Maruthupandiyar Malayalam: Represents the level MDA of normal experimental mast.
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Coma silvery white the tuberous root is dark —brown. Group II Mosquito coil exposed rats showed a significant Coma silvery white, tortuous with transversely cracked and increase in the level of MDA when compared to group 1 rats. It has a strong central vasculature Group III mosquito coil exposed rats treated with Hemidesmus and a pleasant smell and last. Significantly decreased in the level of MDA when Habitate: Throught India compared to group II.
Roots, Leaves, Stem rats. Experimental Designs GSH Body weight at animals was rewarded and they were divided The present study was carried out to evaluate the mosquito coil into 3 groups at 6 animals each as follows: Group I Normal animal received normal diet and water adli bitum Table 2: Represents the levels of GSH in serum of normal and experimental rats.
After the Group III mosquito coil exposed rats treated with Hemidesmus completion of experimental regent the rats were test overnight indicus significantly increased in the level of GSH as and blood samples were collected by the puncturing the retro compared to group II orbital pluxes under light either anesthesia.
Serum was used for the analyses of various biochemical parameters. Protein Bio Chemical Estimation Table 3: Represents the levels of protein in serum of normal and The serum urea was estimated by the method of Berthelot experimental rats. Malondialdehyde was estimated by the Group II mosquito allethriin exposed rats showed a significant thiobarbituric acid assay method of Beuge and Aust  decreased in the level of protein when compared to Group I Reduced glutathione was estimated by method of Moron sgpr rats.
Group III mosquito aplethrin exposed rats treated with Hemidesmus indicus. Data was Hemidesmus indicus on protein in experimental rats. Represents the activity of SGPT in serum of normal and experimental rats. Mosquito coils are often used Group II mosquito coil exposed rats showed a significant overnight in sleeping quarters, where continuous exposures increased in the activity of SGPT when compared to group I may occur.
Exposure to coil smokes occurs during rainy rats. Group III mosquito coil exposed rats treated with periods because mosquitoes are found to be more active in the Hemidesmus indicus.
Significantly decreased in the activity of environment due to collection of water and increase due to SGPT as compared to group II. Table 5 effect of Hemidesmus collection of water and increase in green plants Liu, .
This exposure causes the potential toxicological effects of the smoke on humans. Hence the present study aims to evaluate Urea the toxicity of allethrin based mosquito coil smoke on various biochemical Parameters.
The results of bio chemical analysis Table 6: Represents the levels of urea in serum of normal and in human exposed to mosquito coil smoke are shown in table 8. Group III mosquito coil exposed rats treated with Hemidesmus In the present study increased MDA content in mosquito coil indicus significantly decreased in the level of urea when exposed rats as compared with control rats. The increased compared to group II.
Table 6 effect alethrin Hemidesmus indicus MDA content in mosquito coil exposed rats provide relevant on urea in experimental rats. We found that mosquito coil exposed subject dgpt in an increase of Albumin plasma MDA, indicating lipid oxidation. Supplementation of Hemidesmus indicus to mosquito coil exposed rats Table 7: Represents the level of Albumin in serum of normal and decreased the MDA content indicates the allethrun oxidative experimental rats.
Compounds, such as free radicals and hydroperoxide glutathione, such as of free radicals Group II mosquito coil exposed rats showed a significant and hydroperoxide glutathione status is a highly sensitive decreased in the level of Albumin in serum when compared to indicator of cell functionality and viability, GSH depletion is Group I rats. Group III mosquito coil exposed rats treated with linked to a number of disease states cancer, neurodegenerative Hemidesmus indicus significantly increased in the level of disease cardio vascular diseas.
Table 7 effect of decreased content of as it in mosquito coil exposed rats as Alletbrin indicus exposed rats on albumin in experimental compared to control rats. The decreased plasma GSH content, rats. Bilirubin Administration of Hemidesmus indicus mosquito coil exposed Table 8 represents the levels of Bilirubin in serum of normal rats increased the GSH content indicates the sgtp in and experimental rats. Group II mosquito coil exposed rats antioxidant defence.
Summary and Conclusion increment allethhrin which are excess breakdown of blood Chemical pesticides are one of the major sources of protein and increase in tissue protein catabolism.
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Thousands of new chemical could have resated from the inflammatory process taking place formulations are synthesized introduced and widely used in as a result of irritation of various organs by toxic chemical best control programs. Mosquito coils are widely used to from coil smoke cyanide, which is released in mosquito coil prevent from mosquito bite and from entering the room.
The smoke is known to cause reduced oxygen carrying capacity of burning of mosquito coil to generates large amounts of sub erythrocytes, leading to reduced metabolism and consequently micrometer particles and gaseous pollutants. These particles result in reduced energy output which may explain the body can reach the lower respiratory tract and may be coated with a weakness. The sneezing that resulted after 6 days exposure wide range of organic compound.
The long term exposer of could be the irritants released, sulphates and polycyclic mosquito coil smoke can cause potential toxicological effects aromatic hydrocarbons  An decrease in total protein and on rats. The from the public and medical profession due to greater inflammation may cause damage to the liver cells which are advances in the understanding of the mechanisms by herbs sites of the protein synthesis leading to decrease in synthesis of positively influence health and quality of life several plant protein.
Thereby causing is decrease in the amount of protein products are known to exhibit creditable medicinal properties Liu et al. The present study aims to analyse the effect of Hemidesmus indicus on various biochemical Urea parameters in mosquito coil exposed rats supplementation with In the present study increase level of urea was observed in Hemidesmus indicus on mosquito coil exposed rats exerts the mosquito coil exposed rats as compared to control rats.
Carbamoyl transferase and orginase peroxidation and improve the antioxidant status.
Cycle is confined to the liver. Also indicate kidney damage however, SGPT. Studies The smoke also elevated the liver enzymes activities. The aimed at producing alternative mosquito repellents with elevation in the activities of these enzymes sussested.
Liver minimal toxicity affects should be an area of practical interest. Previous studies indicated that ALT is found in Supplementation of Hemidesmus indicus to mosquito coil high concentration in the hepatic. Tissues of dogs cats and exposed rats reduce the toxic effects of mosquito coils. Arch occup environ health ; Secondary In the present study, the level of bilirubin increased in metabolites of chrysanthemum genus and their biological mosquito coil exposed rats as compared to control rats.
The increased level of assessment of the toxicological properties of pyrethroids bilirubin indicate. The increased level of bilirubin indicate the and their newrotoxicity.
Crit Rev toxicol ; liver damage. This is confirmed by increased activity of SGOT 21 2 9: Blood urea in the 3. The wealth of India raw materials. Azizi Bo, Henry RL. The effect of indoor environmental the increment among which are excess break down of blood factor on respiratory illness.
Primary school children kaula protein and decrease in tissue protein catabolism similarly high Lumpur; int J Epidemiol. Damage to the 5. Report chim Appl ; 1: The thiobarbituric acid assay.
Sensitization risk of pyrethroid insecticides. Amount of white 9. Occupational exposure to permethrin during its use as a public hygiene insecticide. Ann occup HYG ; Metabolic fate of pyrthrin I Pyrethrin II, and allethrin administered orally to rats. Antioxidant Flavnoids Structure, function and clinical usage. Alternative med ; 1: Levels of glutathione, glutathione reductase and glutathione — s — transferase activities in rat lung and luen. Biochemical et Bio physica ACta, Sangyo eiseigaku zasshi ; Pyrethroid poisoning J assoc physicians India.